MIC 4124 Study Guide - Quiz Guide: Necrotizing Fasciitis, Group A Streptococcal Infection, Streptococcus Pyogenes

• School: University of Ottawa
• Department: Microbiology and Immunology
• Course: MIC 4124
• Professor: Thien Fah Mah

Document Summary

Pathogenic bacteria: location matters: anatomical location/organ determines type of disease, relatively few prompt pathogens and commensal pathogens are more common, disease arises when the host"s protective immune mechanisms are compromised and the organism in icts damage on the host. Staphylococcal infections: spherical gram-positive bacteria that form irregular clusters like grapes. Clinically, can be divided into those that produce coagulase, an enzyme that coagulates (clots) brin in blood, and those that do not: staphylococcus aureus. Most pathogenic and is a common resident of nasal passage. Contains 300 k more bp in genome than s. epidermis (mostly virulence factors) pathogenic strains are coagulase positive. Once it infects the skin, it will stimulate a vigorous in ammatory response (macrophages and neutrophils) It has several ways to evade these host defenses. Survives in phagosome secreted proteins can neutralize amp. Streptococcal infections: spherical gram-positive bacteria that grow in chains, cause a wide range of diseases beyond skin infections (meningitis, pneumonia, etc. , streptococci establish disease.