BPS 1101 Study Guide - Final Guide: Mepyramine, Rofecoxib, Phenacetin

• School: University of Ottawa
• Department: Biopharmaceutical sciences
• Course: BPS 1101
• Professor: William Ogilvie

Document Summary

Doctors approval vs no prescription needed (some are behind the counter) Otc medication are mostly used, cheaper, cost visible. Pain relievers is the most common medicine bought. Hippocrates believed willow was good for child birth. The knowledge of herbs lost in dark ages. He was a rector in church of england. Willow has a bitter taste similar to quinine. Malaria was found in swamps, you have a fever when you"re infected with malaria etc. Willow : dried bark, turned bark into powder and given for fever. 1. 5 kg of bark made only 30g of powder (teaspoon) Salicylic acid made from salicin (salicin is synthetic) 58 billions tablets requires 2 million tonnes of bark. Salicylic acid made and sold by dye company. Bayer started as dye company (paints and dye) Has a bitter taste and causes stomach irritation. He then decided to fix the drug (bitter taste, stomach irritation) Succeeded but was then not effective for pain.