HLSC 2130U Study Guide - Final Guide: Passive Immunity, Vaccine, Infection Control
6 Dec 2018
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Innate and adaptive: innate first and second lines of defense, adaptive third line of defense. First line of defense: chemical and mechanical barriers, chemical salt, lysozymes, hcl, sebaceous secretions, ph, mechanical mucous membranes, skin, normal flora. Ingest and eliminate materials: extract immunological information, phagocytes: macrophages, neutrophils, monocytes, 2. ) Inflammation: four signs, rubor redness, callor warmth, swelling, pain, 3. ) Interferons activate macrophages and nk cells: 4. ) Fever: benefits of a fever include, limits replication of pathogens, reduces nutrition by reducing iron, speeds up cell production. Third line of defense: involves b (antibodies) and t cells, t cells are cell mediated and directly destroy foreign agents, b cells are antibody mediated and are specific. Vaccine types: 1) whole cell weakened or dead, 2. ) Subunit antigenic portion of the organism (not nuclei acid : 3. ) Conjugated contains antigenic portion and proteins to make antigen) the ir stronger: 4. ) Toxoid vaccines derived from the toxins of the organism (tetanus)
