MICB 202 Study Guide - Final Guide: Vancomycin-Resistant Staphylococcus Aureus, Antimicrobial Resistance, Dna Gyrase
Document Summary
Antibiotic- drug used in the treatment and prevention of bacterial infections. Bacteriostatic antibiotics inhibits bacterial growth w/o directly killing it: state the origin of most antibiotics used to treat bacterial infections in humans. Initially differentiated from synthetic compounds because they were natural products derived from microorganisms. ie. penicillin is derived from eukaryotic fungus. Penicillium: state the basic chemical nature of antibiotics. They are small organic molecules with diverse structures and different ones work in different ways: describe the ways various antibiotics work, some interfere with cell wall synthesis by inhibiting transpeptidation reactions during. To be clinically useful, it must be able to affect the bacteria but not affect human cells: explain why -lactam antibiotics and vancomycin kill bacteria. It interferes with pg synthesis; new pg has to be added for bacteria to be able to divide. It binds to an inhibiting enzyme that forms the amino acid cross-links between the glycan chains.
