BIOL373 Study Guide - Midterm Guide: Blood Pressure, Symporter, Collecting Duct System
11 Apr 2017
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Unit 4d: integrated control of fluid and electroyte. Balance: organ responsible for na+ excretion: kidney, cl moves across if only na is regulated via. Electrochemical gradient, nkcc, nacl symporters: homeostatic responses to excess nacl ingestion: baroreceptor reflex response, na+ is regulated by hormone aldosterone. Reabsorption is regulated only through distal nephron: aldosterone is synthesized in: Regulated by avp: 2 primary stimuli for aldosterone release. Increase in plasma: decrease in blood pressure, aldosterone secretion pathway. Blood pressure-> ras pathway-> adrenal cortex-> aldosterone-> p cells of collecting duct-> na reabsorption, K secretion: 2 conditions about potassium homeostasis. Cell hyperpolarizes= muscle weakness: renin- angiotensin system pathway & location of synthesis. In kidney at distal nephron: juxtaglomerular apparatus regulation of gfr: 2 ways. Macula densa: modified tubular epithelium that release paracrine factors that act on smooth muscles. Granular cells: modified anterior wall that cans secrete renin.
