BIOL303 Study Guide - Midterm Guide: Inner Cell Mass, Wnt Signaling Pathway, Epiblast
18 May 2013
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Do not mix up primary neurulation (differentiation of neural plate (4 steps)) and neural cells differentiation. Be able to draw amphibian egg (indicate where gastrulation starts, which layers form = extrapolation to other species) Dorsal blastopore lip (spemann"s organizer) equivalent in birds in hensens node: whole blastopore lip = primitive streak. Large micromere b-catenin = mesoderm of sea urchin = wnt signalling pathway. Cell movement ingression (few cell come out of layer) vs. delamination (2 layers from. 1 so several cells separating: ingression large micromeres, delamination bird epiblast. Epiboly = cell movement on outer surface. Involution spread of cells on the interior. Amphibian gastrulation 2 simultaneous processes involution (form mesoderm), epiboly (form ectoderm)*** Cellularization of blastoderm in drosophila = cells have receptors = tight control. Mc questions: gurken (ligand) dorsal/ventral polarity in drosophila gurken determine fate of follicular cells to become dorsal which then influence the embryo to dorsalize.
