BIOL239 Study Guide - Final Guide: Chromosome Segregation, Zygosity, Genetic Linkage
5 Jul 2015
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What did they study? studied peas, worked with model organisms, ratios. Worked with chromosomal theory of inheritance with the fruit fly. Allowed homozygous white eyed to cross with hemizygous red-eyed. Studied recombination frequencies and worked with genetic mapping. Concluded that x and y chromosomes determined sex phenotype. Discovered gene determining eye colour on the x chromosome. White eye male among red eyd flies. Recombination frequencies can be used as a gauge of the physical distance between two genes on the same chromosome ( linked) Determined the order of genes on the same as stern but with corn chromosome. Physical markers abnormalities and used genetic markers as point of reference for recombination. Identified nuclein as a weakly acidic, phosphorous rich material from the nuclei of human wbc. Studies with streptococcus (s) smooth wildtype and (r mutant (avirulent) Transformation in vitro growing live r-type bacteria in the presence of dead s cells.
