BIOL130 Study Guide - Sister Chromatids, Restriction Point, Cytokinesis

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Mitosis: division of genetic material that produces daughter cells genetically identical to parent cell; accompanied by cytokinesis (division of the cytoplasm into 2 daughter cells) Meisosis: division of genetic material to produce daughter cells with half the hereditary material found in the parent cell; produces gametes (eggs and sperm); basis of sexual reproduction. Eukaryotic chromosomes: multiple linear chromosomes housed in nucleus; 2 copies of each essential to survival; complex packing of dna. Dna packaging: dna double helix wrapped around histone proteins; tightly packed dna with histones; chromosomes condense to prepare for mitosis/meisosis. Control of the cell cycle: mitosis-promoting factor (mpf) is a heterodimeric protein that induces mitosis. Cyclins, cdks: cdk: transfers phosphate from atp; not active unless bound to cyclin partner; constant levels, cyclins: regulatory subunit; levels change thru cell cycle. G1/s (restriction point): checks if dna is undamaged, if size of cell is big enough to split; nutrition; checkes external signal molecules.

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