MCIM 321 Midterm: Midterm 1

• School: U of S
• Department: Microbiology and Immunology
• Course: MCIM 321
• Professor: Bretscher Peter

Document Summary

1-2: historical introduction and overview of the course. Voltaire reported the chinese custom of taking dried powders of smallpox crusts, preventing the contraction of the disease later in life. Circassians practiced a form of vaccination; gave their children smallpox in their infant years to protect their life and beauty: first reports of prophylactic immunization immunization that can prevent an infectious disease. Killed organisms are unlikely to deplete the vital foodstuff. Roux and yersin showed that a bacterium free filtrate of the diptheria bacillus contains exotoxin and if given to an animal, could cause its death. Immune serum serum obtained from an immune animal. Administration to normal unimmunized animals conferred resistance: passive immunization the attainment of protection by an unimmunized individual upon the transfer or either serum or cells from an immune individual. Demonstrates that there are protective molecules in immune serum: antibodies protective molecules in immune serum, antigens molecules/substances to which antibodies specifically bind.