PSYC 3030 Study Guide - Final Guide: Short-Term Memory, Nucleus Accumbens, Opioid Receptor

• School: University of Guelph
• Department: Psychology
• Course: PSYC 3030
• Professor: Boyer Winters

Document Summary

Marijuana-mixture of dried leaves and flowering tops (resin) Thc and its metabolites accumulate in adipose tissue via depot binding. Basal ganglia: striatum, globus pallidus, substancia nigra, etendopeduncular nucleus. Increased hunger, motor effects, cognition and decision making. Synthesized from arachidonic acid: a fatty acid found in membrane phospholipids. Too lipid soluble to be stored in vesicles, made and released when needed. Synthesis is triggered by an increase in calcium. Increase in pyramidal cell excitability in certain areas of the hippocampus. In the ca1 region of the hippocampus: gabaergic neurons: involved in integrating information processing, pyramidal neuron. Lower doses: buzz, period of light-headedness and tingling in extremities, high, euphoria/exhilaration, disinhibition (giggles, stoned, calm/relaxation, come down, diminishing effects as drug is removed from blood and metabolized. Physiological responses: warmth/flushing (increased blood flow to skin), increased heart rate, increased appetite. Cb2 receptors and parallel mechanisms also at work. Most effects are abolished in cb1 receptor ko mice.