PSYC 2410 Study Guide - Final Guide: Reuptake, Catecholamine, Acetylcholine

• School: University of Guelph
• Department: Psychology
• Course: PSYC 2410
• Professor: Elena Choleris

Document Summary

Transmission of signal from one neuron to another. Electrical synapses faster, membrane coupling, direct transmission. Neuron glial cells, including tripartite synapses (astrocyte foot around chemical synapses) In general, electrical synapses seem to help synchronize and coordinate the action of multiple neural cells in a particular area. Many neurons synthesize and release one neurotransmitter, but there is often coexistence between. Bigger peptides/proteins: somal vesicle packaging, then active axoplasmatic transport (~40 cm/day) Small molecules: axonal travel usually passive (concentration gradient), button vesicle packaging. Presynaptic vesicles fuse (dock) with the cell membrane. Membrane receptors o: metabotropic, cytosolic, nuclear. Receptor: a protein that contains the binding site for a specific neurotransmitter (ligand) Receptor subtypes: e. g. dopamine has 5 receptor subtypes; d1, d2, d3, d4, d5. Excitatory post synaptic potentials (depolarization): often na+ channels. Inhibitory postsynaptic potentials (hyperpolarization): often k+ or cl- channels. Metabotropic receptors on the pre-synaptic neuron terminal region, soma, or dendrites. Often affect intracellular processes (e. g. in terminal neurotransmitter release)