POPM 3240 Study Guide - Quiz Guide: Statistical Significance, Recall Bias, Blind Experiment

• School: University of Guelph
• Department: Population Medicine
• Course: POPM 3240
• Professor: Cathy Bauman

Document Summary

Used to investigate whether or not one intervention method is better than another. A type of experimental study: some sort of intervention. Different from observational, in which you just observe outcome. Useful for evaluating new forms of treatment (ex. drugs) Prophylactic/preventative studies: assess efficacy of vaccines or feed additives. Therapeutic studies: assess efficacy of antibiotics or anti-cancer drugs. Procedure: clear hypothesis, define target population, define study population, random assignment, group a treated, better, not better, group b treated (same time as group a, better, not better, follow up outcomes, statistical analysis, interpretations and conclusions. Look at disease in a controlled, clinical environment (usually hospital) Subjects are treated and followed up for their condition. Challenge trials: subjects exposed to a particular factor of interest. Does(cid:374)"t take i(cid:374)to a(cid:272)(cid:272)ou(cid:374)t fa(cid:272)tors/e(cid:454)posures prese(cid:374)t i(cid:374) the real (cid:449)orld. Evaluate whether procedure/treatment can prevent disease in those who are disease-free at the start of the study. More applicable to real-world more relevant.