MBG 3060 Study Guide - Final Guide: Meiosis, Gene Therapy, Antibody

• School: University of Guelph
• Department: Molecular Biology and Genetics
• Course: MBG 3060
• Professor: Andrew Robinson

Document Summary

Inbreeding: the probability that an individual is homozygous at a locus because: 1: some of their ancestors were related. Identity by descent : they come from a small population and everyone is related even if the family tree doesn"t go back far enough to show it. Identity by state : now we"ll be a bit more scientific. Inbreeding coefficient: proportion of loci in an individual that have both alleles identical by descent or by state. Or : proportion of individuals in a population whose alleles at a given locus are identical by descent or by state. Individuals may have several common ancestors: each one contributes a separate probability that the allele in x are copies of the same ancestral alleles, the total probability of alleles identical by descent and by state is: March 2nd look for inc/co/over dominance: can generalize to n1 generations between a parent and common ancestor and n2 generations between other parent and common ancestor, a.