MBG 2040 Final: Transcription and RNA processing notes
4 Dec 2016
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Dna dependent dnap: refers to the dnap used in replication. Dna dependent rnap: refers to the rnap used in transcription. Rna dependent dnap: refers to the dnap used in reverse transcription. Template strand: the blueprint that enzymes use also called the non coding strand or the antisense strand. Nontemplate strand: also called the coding strand, because the sequence here is identical to that of the mrna (except mrna has u and nontemplate strand has t) also called the sense strand. Sense rna strand: aka pre- mrna also called the primary transcript similar to dna synthesis except that the precursors are ribonucleoside triphosphates (rtps) Atp, gtp, ctp and utp: only one strand of dna is used as a template (template strand, rna chains can be initiated de novo (ie rnap can bind to strand w/out a primer. Tho in euk, transcription factors are needed first) The rna molecule will be complementary to the dna template (antisense) strand.
