MBG 2040 Final: GENETICS EXAM REVIEW

• School: University of Guelph
• Department: Molecular Biology and Genetics
• Course: MBG 2040
• Professor: Baozhong Meng

Document Summary

Watson and crick standard b-form double helix. Meselson and stahl (1958) semi-conservative model confirmed. John cairns replication begins from origin (oric) bidirectionally. Blackbur and szostak yeast telomere structure. Collins human genome project/telomeres linked to aging. Basic features of dna replication in prokaryotes. Dna polymerase ii, iv, and v are required for dna repair functions. (dnmp)n + dntp ---- (dnmp)n+1 + ppi. Replication fork drawn in assignment 5 q. Comparison of dna replication in prokaryotes vs eukaryotes. Linear but larger genomes, only occurs in s phase, shorter primers and okazaki fragments, multiple dna polymerases, also bidirection but from multiple sites, slower, etc. Basic features of dna replication in eukaryotes. Perpetuation of genetic info via dna replication. Review the differences of transcription in prokaryotes and eukaryotes from. General features of rna synthesis no primer is required, involves rnps, Transcription start site (+1) located 5-9nt downstream from the -10. Pomoter region: -35 ttgaca sequence and -10 tataat sequence on.