MBG 2040 Midterm: MBG 2040 Midterm Study Notes

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Genetics plays a critical role in understanding disease. Genetics used biotechnology industry for drug design, development, and production: check out ted talk link posted on courselink. A gene is the fundamental unit of heredity. Genes come in multiple forms called alleles. Genotype confers phenotype (most of the time) Genetic information is transferred to rna to protein. Gregor johann mendel discovered basic principles of heredity: principle of segregation (1st law) and independent assortment (2nd law) The pea plant pisium sativum: complete generation single growing season. Produce many offspring: enabled calculation meaningful mathematical ratios. Several traits existed 2 easily distinguished forms. Mendel"s first law: principle of segregation: each individual organism possess two alleles encoding a trait, alleles separate when gametes are formed, alleles separate in equal proportions. Symptoms: severe anemia, debilitating muscle pain, respiratory problems. Admitted hospital 1904 under care of intern dr. ernest irons and supervising physician dr. james herrick. Performed blood smear as part of diagnostic attempts.

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