BIOM 4180 Study Guide - Comprehensive Final Exam Guide - Protein Kinase A, Heart Failure, Adrenergic Receptor

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Lecture 1: heart valves: blood flow thru the heart (review) Inferior and superior vena cava -> right atrium -> tricuspid valve -> right ventricle -> pulmonary valve -> pulmonary artery ->lungs -> pulmonary vein -> left atrium -> mitral valve ->left ventricle -> 2 types of valvular disease: regurgitation: valve isn"t fully closed, so blood moves backwards. There is a normal amount of regurgitation, but it should not be excessive. In the following slide, there are 2 images. In the left image, you can see 3 obvious leaflets, and there is obvious overlap. In the right image, there are 4 leaflets, and there is a hole in the intersection of the leaflets: causes, genetics, chordae tendonae is damaged, and doesn"t close the valve properly. If the valve prolapses (opens in the other direction) instead of being shut, blood will move backwards.

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