PAT 20A/B Study Guide - Final Guide: Insulin Receptor, Portal Venous System, Glucose Transporter

• School: Ryerson University
• Department: Pathotherapeutics
• Course: PAT 20A/B
• Professor: Leo Michelis

Document Summary

Insulin is the only hormone known to have a direct effect in lowering blood glucose levels. Action of insulin : promotes glucose uptake by target cells and provides for glucose storage as glycogen. Insulin acts to promote fat storage by increasing the transport of glucose into fat cells. Insulin inhibits: the intracellular breakdown of stored triglycerides protein breakdown. Increases protein synthesis by increasing the active. Insulin gets more amino acids into the cells which increases protein synthesis. When there is enough insulin present, protein breakdown is minimal b/c the body is able to use glucose and fatty acids as a fuel source. Secretion of insulin occurs in a biphasic fashion ( having 2 phases) Serum insulin levels begin to rise within minutes after a meal, reach a peak in approx. 30-45 minutes, and then return to baseline levels within. Insulin secreted by the beta cells enters the portal circulation and travels directly to the liver approx.