[PHAR 100] - Final Exam Guide - Everything you need to know! (130 pages long)

• School: Queen's University
• Department: Pharmacology and Toxicology
• Course: PHAR 100
• Professor: Bill Racz

Document Summary

Sorcerers were thought to be responsible for all evil events that befell the group. Healer gave each member a poison and those that vomited the poison survived and those that died were sorcerers. Natives dipped their arrow tips into a poison curare, which cause paralysis by inhibiting ach at the neuromuscular junction. Derivatives of curare are used today in surgery as a muscle relaxant. Fungus on rye produces alkaloids usually during wet seasons plant disease which can produce toxicities in humans. 12,000 in one area of russia died not recognized at the time (ergot poisonings) Symptoms of ergot poisoning: burning in limps st. anthony"s fire monks set up hostels to care for patients. Abortion ergot causes violent contractions of the uterus; used by midwives. Ergotamine a more modern use is for migraines because it constricts blood vessels. Ergonovine once used to contract the uterus to hasten delivery, but it is too dangerous and this is no longer used.