MUSIC 1A03 Study Guide - Final Guide: Staphylococcus Epidermidis, Staphylococcus Aureus, Candida Albicans
Document Summary
Thin outer portion consisting of several layers of epithelial cells. When unbroken, an effective physical barrier against microbes in the environment. Thick inner portion; provides strength and flexibility; supports growth of epidermis. Blood vessels (high level of vascularization), nerve endings, hair follicles, sweat & oil glands. Follicles and glands can serve as passageways for microorganisms to gain access to deeper levels of the dermis. More severe infections as you move deeper. High levels of vascularization can disseminate and move to other areas of the body. Skin"s surface can be an inhospitable environment for microbial growth. Covered in salt, sweat and sebum (containing antimicrobials) Outer layers of the epidermis sloughed off and replaced ~1 month. Normal flora has to tolerate the renewal and must persist in this process. Normal flora must be resistant to drying and high salt concentration. Over 200 species of bacteria comprising normal skin flora; mainly gram positives and some yeasts (e. g. candida albicans)
