LIFESCI 2A03 Study Guide - Midterm Guide: Biological Immortality, Axolotl, Planaria
4 Nov 2018
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Could involve formation of scar tissue and deposition of collagen fibres. Regeneration in animals with simple body plans bidirectional regeneration: when cut in half, each piece will regenerate into a new organism can regenerate in both directions fragmentation = clonal asexual reproduction. Ex. planar - when cut at any point, each piece will become an entire new organism. Regeneration in other organisms mono(uni)directional regeneration: regeneration of lost appendages that proceeds distally from cut site. Ex. insects and lower vertebrates (salamanders) if a roach"s leg is cut off, a new leg will grow traditional model organisms for biomedical research. Model organisms: are non human species that are used in labs to help scientists understand biological processes traditional organisms have limited regenerative ability. Piwi2, piwi3, cdh4, p53, cat. 2/3 genes neoblasts tell you there"s a cut and regeneration needs to occur increasing proliferation of neoblasts that gives rise to daughter cells.
