HTHSCI 2H03 Study Guide - Comprehensive Final Exam Guide - Vomiting, Subcutaneous Injection, Pharmacokinetics
20 Nov 2018
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Document Summary
Clients are going to respond to medications differently so that we can advocate for them. The movement of a drug from its site of administration across body membranes and into circulating fluids (bloodstream) Routes of drug administration - refer to chapter 9 (not required, but can read) Topical - applying the drug to the ear where we want to exert a biological effect, we have the privilege to apply the medicine directly where it needs to work. Topical administration to the lungs which are inside the body (the one organ system that can be accessed topically) These are not being absorbed into bloodstream, we"re putting them where they need to be. Hits the liver first (portal), liver metabolizes (a little bit of the drug lost), then systemic circulation, the target tissue. We expect that the patient has a working gi tract, and a working liver. We know that some drug is lost before it reaches the systemic circulation.
