BIOCHEM 3G03 Quiz: 3G03_2012_Test_2_ver1.pdf
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Note: please check your examination booklet to ensure all pages are there. There are 27 questions and 7 pages. Please mark your answers clearly on the examination answer sheet. You can keep the examination booklet. Please also mark your seat number on the scantron in the space for record (seat) Number according to the following table. Failure to indicate your version number or seat number may result in 5% penalty. Table for conversion of row number: For example: w20 is 2320. Glutathione transferase consists of a dimer of two identical subunits. The dimer is in equilibrium with its constituent monomers. Site- directed mutagenesis studies were carried out on this protein in which two arginine residues were mutated to glutamines and two aspartates were mutated to asparagines. These substitutions caused the equilibrium to shift in favour of the monomeric form of the enzyme.