BIOCHEM 3G03 Study Guide - Quiz Guide: Myoglobin, Methemoglobin, Heme

• School: McMaster University
• Department: Biochemistry
• Course: BIOCHEM 3G03
• Professor: Daniel Yang

Document Summary

Keratin filaments constitute the bulk of animal hair. Collagen is a major protein in connective tissue. Myosin interacts with actin to facilitate muscular movement. Kinesin moves along microtubules to support a variety of cellular functions. Ai(cid:396) does(cid:374)"t dissol(cid:448)e i(cid:374)to (cid:449)ate(cid:396) (cid:449)ell so (cid:449)e (cid:374)eed a (cid:373)e(cid:272)ha(cid:374)is(cid:373) fo(cid:396) this. O2 binding proteins increase the solubility of o2. Myoglobin contains a polypeptide chain plus the iron-containing porphyrin derivative called heme. Heme is a type of prosthetic group, an organic compound that allows a protein to carry out a function that the polypeptide alone cannot perform in this case, bind o2. Fe(ii) binds o2 but fe(ii) prevented from being fe(iii) by restricting access of o2 to fe(ii) By itself, heme is not an effective oxygen carrier because the central iron atom is easily oxidized. (cid:271)ut (cid:449)he(cid:374) the he(cid:373)e is pa(cid:396)t of a p(cid:396)otei(cid:374) like (cid:373)(cid:455)oglo(cid:271)i(cid:374) o(cid:396) he(cid:373)oglo(cid:271)i(cid:374), o(cid:454)idatio(cid:374) does(cid:374)"t readily take place.