BIOCHEM 2EE3 Study Guide - Final Guide: Opsin, Pyridoxal, Pantothenic Acid
23 Apr 2016
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Document Summary
Standard aa from which proteins are made up of have a few functional groups which help them be specialized. Certain reactions can only happen in the presence of association of cofactors. Cd2+, hg2+, zn2+ are trace elements that act as cofactors. Cd2+ or hg2+ would make the enzyme inactive. Reversible changes of oxidation state of the metal ion makes it a catalyst. It acts as an electrostatic stabilizer because it shields negative charge. 1/3 of all enzymes require presence of mental ion. !1 cytochrome oxidase oxidation/reduction ascorbic acid oxidase oxidation/reduction alcohol dehydrogenase helps bind nad+ histidine ammonia lyase glutamate mutase aids in catalysis by electron withdrawal co is part of cobalamin coenzyme urease catalytic site xanthine oxidase oxidation/reduction nitrate reductase oxidation/reduction. Coenzymes glutathione peroxidase replaces s in one cystine in active site many kineases helps bind atp. Permanently bound to enzymes via covalent interactions = prosthetic group. Heme of cytochrome c > iron containing group involved in cell respiration.
