PSYC 338 Final: Psyc 338 – Final Notes march 11.docx

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Fragile x syndrome is a genetic condition that causes a range of developmental problems including learning disabilities and cognitive impairment. Usually, males are more severely affected by this disorder than females. Nearly all cases of fragile x syndrome are caused by a mutation in which a dna segment, known as the cgg triplet repeat, is expanded within the fmr1 gene. Normally, this dna segment is repeated from 5 to about 40 times. In people with fragile x syndrome, however, the cgg segment is repeated more than 200 times. Fragile x syndrome occurs in approximately 1 in 4,000 males and 1 in 8,000 females. Maternal rubella infection ( first 8 weeks) 4 systems oxytocin-opiate system amygdala system hippocampal system temporal and parietal association cortex cerebellum/brain stem abnormalities and frontal lobe differences. Hippocampal system- immature neurons and abnormally densely packed neurons these individuals will have affected working memory trouble with interactions.

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