PSYC 211 Study Guide - Final Guide: Securin, Cyclin-Dependent Kinase 1, Nuclear Membrane

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Notes ii: topic 11 - 15 (cell cycle: aikins. Topic 11 introduction to the cytoskeleton and actin. Ex. muscle cells are long, cylindrical, multi-nucleated cells. Epithelial cells come in different shapes and sizes. Simple columnar, simple squamous, transitional, stratified squamous (thin, flattened cells) With the same genetic information, different cells are able to adopt significantly different shapes. Cell has a large degree of internal organization. Apical domains often different from the basolateral domains. Apical domain interacts with the lumen of an organ. Basolateral domain communicates with the extracellular matrix. Cytoplasmic dynein (bring towards centre), kinesin family member (move away) Cell constructs its own polymerized cytoskeleton to allow for organization and motility. Made up of microfilaments (actin filaments), microtubules and intermediate filaments. Lots of diseases associated with intermediate filaments, but there is significantly less known about them (tough to research) Cells can control the shape of the cytoskeleton.

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