PHGY 212 Study Guide - Final Guide: Vaccinia, Thymus, Smallpox
25 Aug 2016
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Primary (involved since birth, lymphocytes form and mature) lymphopoesis site,eliminate self- reactive cells connected by circulatory sytem. Ecf cell-cell or cytokin- cell interaction hub lymphocyte activation yolk sac, fetal liver bone marrow thymus blood stem cells. T-cell maturation birth of b/t cells lymph nodes (filter lymph) spleen (filter blood) Malt: mucosa associated lymphoid tissue (filter tissue fluid) lymph = same content as isf flows in/out of capillaries, drains to blood. Jenner speaks to milkmaids, vaccinia (cow disease) hands are pockmarked. = immunogen hapten (+carrier = immunogen) tolerogen = only your own body. 3 lines of defense against antigens coverings: skin/mucous. Response transfusions reproductive immunity of mother to baby. 2 processes humoral innate: no memory cellular adaptive. Elisa (enzyme linked immunosorbent assay) complement mediated lysis agglutination assay diagnose exposure to disease test for presence of antibodies in serum. 3 + control antigen or antibody bind to hemagglutination if rbc is source plastic well walls of antigen.
