IMED1001 Study Guide - Final Guide: Enzyme, Osteoclast, Bone Resorption
IMED1001: Lecture 7 Notes:
Cartilage:
-Has tough matrix !
-Consisting of fibres, glycosaminoglycans (GAG) in ground substance!
-Helps with resisting compression!
-Processing: cells will shrink more than matrix!
-Lacunae: appear to be in small cavities!
-Lacunae is a characteristic feature of cartilage !
-During life: cells in contact with surrounding matrix!
Types of Cartilage:
1. Hyaline cartilage!
-Glassy appearance !
-Matrix is homogenous!
-Matrix looks transparent!
-Fibres present but not visible!
2. White fibrocartilage !
-Lots of collagen in the matrix!
-Gives it the white appearance!
-Collagen fibres can be seen!
3. Elastic cartilage!
-Abundance of elastic cartilage visible in matrix!
-Stained dark!
Hyaline Cartilage:
-Fibres are present in matrix but cannot be seen!
-Avascular: has no BV in cartilage!
-Perichondrium = fibrous covering: carres BV!
-Chondrogenic cells are undifferentiated cells in deeper parts!
-Chondrogenic cells -> chondroblast -> produce matrix !
-= growth by apposition!
Interstitial Growth of Hyaline Cartilage:
-Division of deeper chondrocytes!
-Chondrocytes produce new matrix!
-Cell nests and isogenous groups formed!
-Cells born of single parent cell!
-Own matrix separates them!
-New matrix that s produced is bluish = territorial matrix!
White Fibrocartilage:
-Lots of collagen!
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