BIOL122 Study Guide - Final Guide: Anaerobic Respiration, Chest Pain, Ischemia
Document Summary
Cigarette smoke contains toxin which irritates and damage the endothelial lining of vessel"s wall. For angina chew aspirin at the start of pain in the chest/to reduce thrombus formation. Gtn (glyceryl trinitrate) sublingually for quick absorption/effect to vasodilate blood vessels. A blocker or calcium channel blocker may also be given to reduce force of contraction of the heart. Anticoagulants eg. heparin administered iv for quick effect. Aspirin to inhibit platelet aggregation via inhibition of the cyclooxygenase (cox) pathway enzyme by blocking the formation of thromboxane. Anticoagulant such as warfarin to stop clotting factor production or heparin to reduce fibrin production. Beta blocker or calcium channel bloker (atenolol, metoprolol, nifedipine). Statin drugs (hypocholesterolaemic) e. g lovastatin, simvastatin, atorvastatin reduced blood cholesterol by blocking a key enzyme in cholesterol synthesis in the liver. Reduce blood cholesterol by blocking a key enzyme (hmg coa) in cholesterol synthesis in the liver.
