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16 Nov 2019
The carbonate buffer system is very important in regulating blood pH levels. Carbonic acid is diprotic and therefore has two Ka values: H_2 CO_3 (uq) H^+ (aq) + HC0_3 (aq) K_a 1 = 4.2 times 10^-7 HCO_3 (aq) H^*(aq) + CO_3^-2 (aq) K_a 2 = 4.8 times 10^-11 Since the second dissociation has a K_a value significantly smaller then that of the first dissociation, it can be assumed to have no effect on the H_2 CO_3 (aq)/HCO_3^- (aq) equilibrium. The pH of blood is 7.4. What is the ratio of carbonic acid to bicarbonate ion in blood?
The carbonate buffer system is very important in regulating blood pH levels. Carbonic acid is diprotic and therefore has two Ka values: H_2 CO_3 (uq) H^+ (aq) + HC0_3 (aq) K_a 1 = 4.2 times 10^-7 HCO_3 (aq) H^*(aq) + CO_3^-2 (aq) K_a 2 = 4.8 times 10^-11 Since the second dissociation has a K_a value significantly smaller then that of the first dissociation, it can be assumed to have no effect on the H_2 CO_3 (aq)/HCO_3^- (aq) equilibrium. The pH of blood is 7.4. What is the ratio of carbonic acid to bicarbonate ion in blood?
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manoj0901Lv2
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Hubert KochLv2
16 Nov 2019
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