Question

The catabolic pathways that degrade fatty acids do not generate ATP directly, but produce NADH and acetyl-CoA. Given what you know about cellular metabolism, which of the following enzymes is required to completely break down fatty acids?

acetyl-CoA carboxylase, which catalyzes the formation of malonyl-CoA from acetyl-CoA

pyruvate dehydrogenase, which catalyzes the formation of acetyl-CoA from pyruvate

fumarase, which catalyzes the conversion of fumarate to malate in the TCA cycle

lactate dehydrogenase, which catalyzes the fermentation of pyruvate into lactate