Question

1. The drug amphetamine (molecular weight of 135.2) is often supplied as the phosphate salt of the form B•H₃PO_{4 .}The drug is supplied in tablets that contain 21 mg of the drug salt and the bioavailability of the drug is 41%. If a person takes 4 tablet(s), what is the effective dose in mg? Report your result to the nearest whole number.

2.The drug amphetamine (molecular weight of 135.2) is often supplied as the phosphate salt of the form B•H₃PO_{4 .}The drug is supplied in tablets that contain 18 mg of the drug salt and the bioavailability of the drug is 51%. If a person takes 3 tablet(s), what is Cp? Assume the volume of distribution is 3.4 L/kg and the person weighs 154lbs. Report in ppb and with 1 decimal place.

3.A drug has a plasma half-life of 4.8 hours. If the peak plasma concentration of this drug is 39.5 μg/L, how much time will elapse before the plasma concentration reaches 10.0 μg/L? Report your result in hours with 1 decimal place.