Question

Well into exercise, the ratio of ATP/AMP in muscle cells decreases. What effect does this ratio reduction have on the activity of phosphofructokinase and pyruvate kinase?

Both enzymes are increased in activity due to lack of allosteric binding of ATP.

Phosphokinase activity is increased and pyruvate kinase is decreased.

Both enzymes decrease in activity due to lack of allosteric binding of ATP.

Both enzymes will remain at the same level of activity to maintain normal glucose metabolism.