I have a exam comming up and i am struglging can you please answer these question in as much details as possible please do not leave small answers, if you going to just write a few sentences and ignore questions pelase do not waste my question as i will just give it a negative review. Please if you just going to answer one part and ignore the other dont answer it. thanks Thank you for helping.
4. Describe a synthesis of the amino acid, 4-chlorophenylalanine 8 from diethylacetamidomalonate 9 and 4-chlorobenzyl chloride 10. State which base is used in the alkylation step, and also which acid is required for hydrolysis and decarboxylation. Draw the structures of all intermediates. Mechanisms with curly arrows are not required. (5 marks) COZEt OH H2N 10 Continued. 5. All five of the ring atoms in pyrrole (f carbon atoms and one nitrogen atom our are sp2 hybridised, with a p orbital perpendicular to the plane of the molecule on each The nitrogen atom in pyrrole has five valence electrons. Using suitable diagrams, explain why pyrrole is aromatic, how it is polarised and why it tends to undergo electrophilic, rather than nucleophilic, aromatic substitution marks)
