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Week 9: Computational modeling of peptides and proteins . Understand and be able to identify different interactions that factor into peptide/protein folding (e-g, hydrogen bonding, salt bridge interactions, disulfide bonding. Be able to predict these interactions given a peptide structure. -Understand basic molecular geometry in a peptide. What is the bond angle between amide N, C, and O atoms? Why is the angle like this? .-What is the geometry like in an alpha helix? What intermolecular forces lead to the formation of a helix? What about for a beta sheet?
Week 9: Computational modeling of peptides and proteins . Understand and be able to identify different interactions that factor into peptide/protein folding (e-g, hydrogen bonding, salt bridge interactions, disulfide bonding. Be able to predict these interactions given a peptide structure. -Understand basic molecular geometry in a peptide. What is the bond angle between amide N, C, and O atoms? Why is the angle like this? .-What is the geometry like in an alpha helix? What intermolecular forces lead to the formation of a helix? What about for a beta sheet?
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