A variety of factors influence enzyme activity. Substances that bind to the enzyme and interfere with substrate binding or catalysis are inhibitors. Identify the type of inhibition associated with each of the following descriptions and examples by sorting each item into the appropriate bin.
The bins are: irriversible inhibition, compenitive inhibition, mixed inhibition
The phrases to sort are:
-Tamiflu, a transition state analog, reversibly binds to neuraminidase
- Inhibitor may perminantely modify an enzyme
-DIPF permanently modifies the hydroxyl group of a Ser residue at the active site
- the AL3+ ion binds to acetylcholinesterase or to the acetylcholinesterase-substrate complex
- binding by the inhibitor does not affect VMax
-Binding by the inhibitor decreases VMax
A variety of factors influence enzyme activity. Substances that bind to the enzyme and interfere with substrate binding or catalysis are inhibitors. Identify the type of inhibition associated with each of the following descriptions and examples by sorting each item into the appropriate bin.
The bins are: irriversible inhibition, compenitive inhibition, mixed inhibition
The phrases to sort are:
-Tamiflu, a transition state analog, reversibly binds to neuraminidase
- Inhibitor may perminantely modify an enzyme
-DIPF permanently modifies the hydroxyl group of a Ser residue at the active site
- the AL3+ ion binds to acetylcholinesterase or to the acetylcholinesterase-substrate complex
- binding by the inhibitor does not affect VMax
-Binding by the inhibitor decreases VMax