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10 Nov 2019
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second messenger cyclic AMP (cAMP) is synthesized from ATP by the activity of the enzyme adenylyl cyclase. Cyclic AMP, in turn, activates protein kinase A (PKA, also called cAMP-dependent protein kinase), which is responsible for most of the effects of cAMP within the cell. Determine the correct steps in the activation of PKA, and then place them in the correct order, starting after the adenylyl cyclase reaction. Not all steps are accurate, and therefore not all steps will be used. Note: if you are marked as incorrect, the red x is for the entire process, not just for the first step. Cytosolic cAMP concentration increases. Two cAMP molecules bind to each PKA regulatory subunit. The regulatory subunits move out of the active sites of the catalytic subunits, and the R2C2 complex dissociates. The free catalytic subunits interact with proteins to phosphorylate Ser or Thr residues. Cytosolic cAMP concentration decreases. Each regulatory subunit is activated as the two cAMP molecules release.
Please Help
second messenger cyclic AMP (cAMP) is synthesized from ATP by the activity of the enzyme adenylyl cyclase. Cyclic AMP, in turn, activates protein kinase A (PKA, also called cAMP-dependent protein kinase), which is responsible for most of the effects of cAMP within the cell. Determine the correct steps in the activation of PKA, and then place them in the correct order, starting after the adenylyl cyclase reaction. Not all steps are accurate, and therefore not all steps will be used. Note: if you are marked as incorrect, the red x is for the entire process, not just for the first step. Cytosolic cAMP concentration increases. Two cAMP molecules bind to each PKA regulatory subunit. The regulatory subunits move out of the active sites of the catalytic subunits, and the R2C2 complex dissociates. The free catalytic subunits interact with proteins to phosphorylate Ser or Thr residues. Cytosolic cAMP concentration decreases. Each regulatory subunit is activated as the two cAMP molecules release.
Patrina SchowalterLv2
6 Aug 2019