EFB325 Study Guide - Peripheral Membrane Protein, Integral Membrane Protein, Beta Barrel

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Lipid bilayer: thin juxtaposed phosolipid molecules that form the cell membrane. Fatty acid: molecule that has a carboxylic acid attached to long hydrocarbon chain. Phospholipid: lipid molecule in cell membranes composed of two fatty acids connected to a polar group. Phosphatidylcholine: common phospholipid in abundance present in most cell membranes. Sterol: subgroup of steroids that have a hydroxyl on the 3rd position of the a ring, amphipathic. Saturated: hydrocarbon tail with no double bonds and full complement of hydrogen atoms. Flippase: flip specific phospholipid from bilayer that faces the exterior to monolayer that face the cytosol. Scramblase: transporter protein that removes randomly selected phospholipids from one layer and insert to another. Integral membrane protein: proteins that are permamnently embedded to the lipid bilayer and removed only by disrupting the bilayer with detergents. Peripheral membrane protein: temporarily attached located in the inside and outside of membrane.

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