BS 375 Lecture Notes - Corynebacterium Diphtheriae, Aerobiology, Mycobacterium Tuberculosis

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Unit 2 part 3 - microbes as a. Aerosolization, aerial transmission and deposition of biological materials. Diseases that may be transmitted via respiratory routes. Aeromicrobiology: study of various aspects of intramural (indoor) and extramural (outdoor) aerobiology in relation to environmentally relevant microorganisms including various bacteria, fungi, and protozoa. Besides these microbes, other biological materials like pollen, insect debris, animal danders (chief source of allergic disorders) are also found in air. Air-borne microbes are important pathogens causing diseases in plants, animals, and humans. A number of allergic disorders are caused by air-borne microflora. Indoor environments: ex. home, occupational surroundings, persons are exposed to fungal allergens. Outdoor environments: ex cereal crops, decaying vegetable matter, organic debris. Very small number of these toxins may become lethal to humans. The "botulinum" a toxin produced by clostridium botulinum is a potential biological warfare agent. The lethal dose of this toxin by inhalation is -0. 3 ug of toxin (death is expected 12 hours after exposure)