BIO Lecture Notes - Humoral Immunity, B Cell, T Cell
2 Nov 2022
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There are two types of lymphocytes, large and small, having almost similar structure. Diameter of large lymphocytes varies from 12 16 m and that of small lymphocytes from 7 10 m). Lymphocytes have a large, round, single nucleus, which almost completely fills the cell. It stains blue very deeply giving ink-spot appearance. The cytoplasm is scanty, i. e. its amount is always less than that of the nucleus. It is seen as a crescent of clear light blue colour around the nucleus. Based on their developmental background, life span and functions, the small lymphocytes have been broadly classified into three subtypes. B lymphocytes which are processed in the bone marrow and concerned with the humoral immunity. T lymphocytes which are processed in the thymus and concerned with cellular immunity. Natural killer (nk) cells are lymphocyte-like cells that non- specifically kill any cell that is coated with immu noglobulin igg. This phenomenon is called antigen-dependent cell-mediated cytotoxicity (adcc).
