MEDICINE Lecture Notes - Rh Blood Group System, Abo Blood Group System, Antigen

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He found two antigens or agglutinogens in red blood cells called a antigen and b antigen. He noticed the corresponding antibodies or agglutinins in the serum called anti a antibody and anti b antibody. Landsteiner"s law: landsteiner"s first law states that, if an antigen is present on rbc membrane, the corresponding anti body will be absent in the plasma, landsteiner"s second law states that if an antigen is absent on the. Rbc membrane, the corresponding an tibody will be present in the plasma. This law is not applicable to rh system. If a particular antigen is present in rbc, the corresponding antibody must be absent in the serum. Based on presence of or absence of antigen a and antigen b, blood is divided into four groups i. e, a, b, ab and o groups. Rh system mainly contains 3 variants c, d, e antigens. The persons having d antigen are called rh+ve. The persons without "d" antigen are called rh-ve.

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