CELS191 Lecture Notes - Lecture 34: Electrophoresis, Microsoft Onenote, Zwitterion
Document Summary
What do these have in common: amino acids are building blocks of proteins, understand the basic structure of amino acids, including their stereochemistry, understand the acid base chemistry of amino acids, understand how electrophoresis is able to separate amino acid, understand how to determine the predominant form of an amino acid in a, nh2 is on the same carbon that the cooh is, chiral carbons always has the same 3d arrangement, all are chiral (can exist as enantiomers) **apart from glycine (has 2 h bonded to chiral carbon) H: view from the side opposite h, the trace nh2 cooh ch3 is anticlockwise, the stereochemistry is (s) (nh2 > ch2 sh > cooh >h, ch2 sh group has higher priority than cooh, prioritization goes in a clockwise direction therefore is an r configuration (only amino acid like this, same arrangement in space for cysteine and alanine but (r)/(s) label is different.
