ENGL 00400SL Lecture Notes - Homologous Recombination, Chromosomal Crossover, Dna Replication
Document Summary
Homologous recombination (hr) is a mechanistically conserved pathway that ensures renovation of genomic integrity. During meiosis, homologous recombination consequences in dna crossover occasions amongst homologous chromosomes that produce the genetic range inherent in germ cells. The bodily connection installation between homologs sooner or later of the crossover occasion is important to facilitate correct chromosome segregation. The importance of homologous recombination can be gauged through the conservation of homologous recombination genes and abilities from micro organism to guy ( mcvey et al,