PCB 3023C Lecture Notes - Lecture 28: Signal Transduction, Cell Signaling, Gene Expression
19 Jun 2022
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Document Summary
Cell signaling unicellular organisms: a free-living cell must be able to track down nutrients, tell the difference between light and dark, and avoid poisons and. Individual cells need to sense and respond to their environment predators: such a cell must be able to communicate with other cells. Later in life, a large variety of signals coordinates the animal"s growth and its day-to-day physiology and behavior. In multicellular organisms, cells must communicate to coordinate function: differentiated cells have different cellular activities. Cell-cell signaling allows cells to communicate to ensure proper tissue and organism function. Cell fates: proliferation, differentiation, migration, cell death, quiescence, the fate of a cell is ultimately determined by cell signaling, cell signaling is influenced by the environment and intracellular signaling. Cell signaling: what"s the point: extracellular signal molecules could change the behavior of a target cell in a large variety of ways, alter the cell"s shape, movement, metabolism, gene expression, or some combination of these.
