Lecture : Lecture 9 Catabolism

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The movement of electrons from an electron source (donor) molecule (reduced) to an electron receptor. Breakdown of larger more complex molecules into smaller, simpler ones. Energy (atp) by substrate level and oxidative phosphorylation. Supply carbon and building blocks: catabolic pathways in the chemoorganoheterotroph. Fermentation: embden-meyerhof pathway also known as glycolysis. Yields 2 atp and 2 nadh: embden-meyerhof simplified glycolysis, pentose phosphate and enter-doudoroff pathways. Produces pyruvate and precursors for rna synthesis and protein synthesis. Can also regenerate gluclose-6-phosphate: what happens to pyruvate, tca or krebs cycle. Product- 2 atp, 6 nadh, and 2 fadh2. Works by releasing excess carbon as co2 (3) 4 nadh and 1fadh2- potential energy (per pyruvate!) 1gtp (atp) this energy is generated. For each pyruvate, 3nadh and 1 fadh2 are produced. 3c pyruvate is converted into 2c acetyl coa. Acetyl coa donates 2c to form 6c citrate. Then gives off co2, energy, and oxaloacetate. For eukaryotes- cristae (inner membrane of the mitochondria)

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