Lecture : Lecture 13 Translation

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Lecture 13 translation: protein synthesis or translation. Converting the sequence of bases on the mrna to a peptide (protein: the players, 70s ribisome (get from powerpoint) made of 30s. 16 s ribosome complementary to shine- dalgarno sequence on mrna which helps to align ribosomes important mrna in the form of codons trna has transfer codons: messenger rna (mrna) Recognition site for ribosome complementary to region on 16s rrna mrna carries code to ribosome; ribosomes are protein factories: transfer rna (trna) three/four leaf clover. Transfer rna; type of rna that carries amino acids to the ribosome. Anti-codon: complementary to codon, has base pairs: recognition of mrna by trna. Anticodon complimentary binds to codon: the genetic code, initiation codon, aug -- codes for formal methionine, stop codons, uga, uaa, uag code for nothing, significance of the reading frame. Incorrect moves back one : asn, lle, pro, thr. These changes are caused by mutation; insertion or deletion: protein synthesis initiation.

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