MICROBIOLOGY Lecture 38: HPV
4 Jan 2022
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Document Summary
Warts, or verrucae (latin verruca, wart), are horny projections on the skin caused by human papillomaviruses. Human papillomavirus (hpv) is the name given to a group of dna viruses that includes more than 100 different strains, some of which are oncogenic (cancer- causing. They differ in the types of epitheliums they infect; some infect cutaneous sites, whereas others infect mucous membranes. More than 30 of these viruses are sexually transmitted and cause genital warts soft, pink cauliflower-like growths that occur on genitalia and around the rectum (figure 38. 21b, c). Genital warts are the most common sexually transmitted infection in the united states today. These viruses have nonenveloped icosahedral capsids with a double-stranded, supercoiled, circular dna genome. At least eight distinct genotypes produce benign epithelial tumours that vary in respect to their location, clinical appearance, and histopathologic features. Warts occur principally in children and young adults, and are limited to the skin and mucous membranes.
