MED Lecture Notes - Lecture 1: List Of One Piece Characters, Succinic Acid, Glyceraldehyde 3-Phosphate
Document Summary
Rate-limiting; committed step; inhibited by atp & citrate; Anaerobic glycolysis; major fate in the lens, cornea, medulla, testes, blood cells. Iv (glucokinase) very rich in liver parenchyma and beta cells of the pancreas. Regulation of pyruvate kinase activity: of and its priming reaction. Dihydroxyacetone phosphate phorylation glucose version to glyceraldehyde 3- phate. 5 triose phosphate isomerase: feedforward regulation by fructose, 1 ,6-bisphosphate. Effect: linkin of 2 pk activities blood glucose. Phosphorylation by camp-dependent protein kinase inactivation of hepatic isozyme pk. Reduction of pyruvate to lactate lactate = product of. Hormonal regulation of glycolysis: short term = allosteric activation/ inhibition phosphorylation/ or dephosphorylation of rate-limiting enyzmes covalent, profound insulin and glucagon effects = superimposed on short-term regulation. High activity = conversion of glucose to pyruvate. Effects of insulin and glucagon on synthesis of ke en me of glycolysis in liver. Pyruvate to acetyl coa produces 2 nadh of pyruvate. G3p; sedoheptulose cl of 1st to c2 of.
