MED Lecture Notes - Lecture 1: Sphingolipid, Terpene, Benzene
Document Summary
A heterogeneous class of naturally occurring organic compounds classified together on the basis of common solubility properties. Insoluble in water but soluble in aprotic/non polar organic solvents (diethyl ether, chloroform, methylene chloride, and acetone) Amphipathic in nature (definition: both polar & non polar) Lipid classes: fatty acids and derivatives, triacylglycerols (tag, wax esters, phospholipids, sphingolipids 6. Open chain forms fatty acids, triacylglycerols, sphingolipids, phosphoacylglycerols, glycolipids, lipid-soluble vitamins (adek) eicosanoids: prostaglandins, leukotrienes, and thromboxanes. Cyclic forms (benzene ring, benadryn rings etc. ) cholesterol, steroid hormones(estrogen,testosterones), and bile acids. Functions of lipids: energy source most impt function. 9 calories per gram fat in the form of tags. Adipose (tag) fatty acids(oxidation) co2 + h2o + *1g protein = 9 cal ; 1g: major component of cell membrane, phosphoglycerides most abundant, sphingolipids, free cholesterol. Main storage form of fatty acids and chemical energy in adipose. Inositol triphosphate and diglyceride for signal transduction (cell to cell communication: sphingolipids.
